Inspired by insights from Reza Hosseini Ghomi
In preventive health and longevity medicine, data is power. Dr. Reza Hosseini Ghomi, a neuropsychiatrist and health technology innovator, recently shared why he personally tracks 12 key biomarkers every six months — not because he is sick, but because he wants to stay well.
His perspective comes from years of treating patients with dementia and neurodegenerative disease, where he observed a common theme: by the time symptoms appear, the biological processes driving disease have often been active for decades.
“I track 12 biomarkers every six months because I spent years treating dementia — and I don’t want to get it.”
— Reza Hosseini Ghomi, MD, MSE
(Source: LinkedIn post, July 2024)
This proactive, data-driven approach aligns closely with Arkaya Wellness’s mission: empowering individuals to prevent chronic disease through early awareness, lifestyle medicine, and measurable action.
Why Biomarkers Matter
Biomarkers are measurable indicators of what is happening inside your body — often long before symptoms arise. Metabolic dysfunction, insulin resistance, inflammation, and cardiovascular disease are now recognized as major contributors to cognitive decline and Alzheimer’s disease.
Tracking biomarkers over time allows you to:
- Detect silent risk early
- Identify trends, not just one-time values
- Personalize nutrition, movement, stress, and medical care
- Shift from reactive care to preventive optimization
The 12 Biomarkers Dr. Ghomi Tracks Every 6 Months
1. Hemoglobin A1C
Reflects average blood sugar over 2–3 months. Elevated A1C is associated with insulin resistance and increased dementia risk.
2. Fasting Glucose
Identifies early blood sugar dysregulation.
3. Fasting Insulin
A sensitive marker for insulin resistance — often abnormal years before diabetes develops.
4. ApoB
Measures the number of atherogenic lipoproteins and is a stronger predictor of cardiovascular risk than LDL cholesterol alone.
5. LDL Particle Number
Provides insight into heart and vascular risk that traditional cholesterol panels may miss.
6. HDL Cholesterol
Protective cholesterol is associated with metabolic and cardiovascular health.
7. Triglycerides
Elevated levels often indicate insulin resistance and poor metabolic flexibility.
8. High-sensitivity C-Reactive Protein (hs-CRP)
A marker of chronic inflammation, which accelerates aging and neurodegeneration.
9. Homocysteine
Elevated levels are linked to vascular damage and cognitive decline.
10. Vitamin D
Low levels are associated with impaired immunity, mood disorders, and cognitive decline.
11. Vitamin B12
Essential for nerve health, cognition, and red blood cell production.
12. Thyroid Stimulating Hormone (TSH)
Thyroid dysfunction can negatively impact energy, metabolism, and brain function.
Dr. Ghomi also notes the value of understanding APOE genotype for contextual Alzheimer’s risk, while emphasizing that lifestyle factors remain powerful modifiers regardless of genetics.
(Source: Reza Hosseini Ghomi, MD, MSE — LinkedIn)
Turning Numbers Into Action
Tracking biomarkers is only meaningful when paired with action.
Dr. Ghomi shared that when his A1C began trending upward, he adjusted nutrition and increased daily walking — successfully reversing the trend. When inflammation markers rose, he refined sleep, stress management, and diet. When cardiovascular markers required attention, he combined lifestyle strategies with appropriate medical therapy.
This cycle of measure → intervene → re-measure is the foundation of effective preventive health.
How Arkaya Wellness Supports Biomarker-Guided Health
At Arkaya Wellness, we integrate biomarker awareness with:
- Lifestyle medicine
- Nutrition education
- Yoga and mindful movement
- Stress regulation and sleep optimization
- Sustainable behavior change
Our goal is not just longer life — but a healthier brain, stronger metabolism, and better quality of life as we age.
Biomarker Tracking Checklist (Client Resource)
Frequency: Every 6 months (or as guided by your clinician)
Metabolic Health
- ☐ Hemoglobin A1C
- ☐ Fasting Glucose
- ☐ Fasting Insulin
Cardiovascular Health
- ☐ ApoB
- ☐ LDL Particle Number
- ☐ HDL Cholesterol
- ☐ Triglycerides
Inflammation & Nutrients
- ☐ hs-CRP
- ☐ Homocysteine
- ☐ Vitamin D
- ☐ Vitamin B12
Hormonal Health
- ☐ TSH
Always review lab results with a qualified healthcare professional.
Sources
- Ghomi, R. H., MD, MSE. LinkedIn post: “I track 12 biomarkers every 6 months…” (July 2024)
- BrainMindedMD.com — Clinical insights on brain health and prevention
Educational content only. Not intended as medical advice.
